(4R,5S)-2-(2-(Diphenylphosphanyl)phenyl)-4,5-diphenyl-4,5-dihydrooxazole
98%
science Other reagents with same CAS 2757082-54-3
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description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-catalyzed asymmetric hydrogenation of prochiral olefins and ketones. Its rigid oxazoline backbone and stereogenic centers enable high enantioselectivity in the synthesis of chiral pharmaceutical intermediates and fine chemicals. Commonly employed in the production of enantiomerically pure active pharmaceutical ingredients (APIs), especially in routes requiring precise stereochemical control. Also applied in palladium-catalyzed cross-coupling reactions where chirality transfer is required. Its diphenylphosphine group facilitates strong coordination to metal centers, enhancing catalyst stability and activity.
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