(4R,5S)-2-(2-(Diphenylphosphanyl)phenyl)-4,5-diphenyl-4,5-dihydrooxazole

98%

Reagent Code: #231805
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CAS Number 2757082-54-3

science Other reagents with same CAS 2757082-54-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 483.54 g/mol
Formula C₃₃H₂₆NOP
inventory_2 Storage & Handling
Storage 2-8°C, Sealed, Dry, Light-proof, Inert Gas

description Product Description

Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-catalyzed asymmetric hydrogenation of prochiral olefins and ketones. Its rigid oxazoline backbone and stereogenic centers enable high enantioselectivity in the synthesis of chiral pharmaceutical intermediates and fine chemicals. Commonly employed in the production of enantiomerically pure active pharmaceutical ingredients (APIs), especially in routes requiring precise stereochemical control. Also applied in palladium-catalyzed cross-coupling reactions where chirality transfer is required. Its diphenylphosphine group facilitates strong coordination to metal centers, enhancing catalyst stability and activity.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿9,630.00
inventory 250mg
10-20 days ฿14,430.00
inventory 1g
10-20 days ฿39,050.00
(4R,5S)-2-(2-(Diphenylphosphanyl)phenyl)-4,5-diphenyl-4,5-dihydrooxazole
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Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-catalyzed asymmetric hydrogenation of prochiral olefins and ketones. Its rigid oxazoline backbone and stereogenic centers enable high enantioselectivity in the synthesis of chiral pharmaceutical intermediates and fine chemicals. Commonly employed in the production of enantiomerically pure active pharmaceutical ingredients (APIs), especially in routes requiring precise stereo

Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-catalyzed asymmetric hydrogenation of prochiral olefins and ketones. Its rigid oxazoline backbone and stereogenic centers enable high enantioselectivity in the synthesis of chiral pharmaceutical intermediates and fine chemicals. Commonly employed in the production of enantiomerically pure active pharmaceutical ingredients (APIs), especially in routes requiring precise stereochemical control. Also applied in palladium-catalyzed cross-coupling reactions where chirality transfer is required. Its diphenylphosphine group facilitates strong coordination to metal centers, enhancing catalyst stability and activity.

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