(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-cyclohexylpropanoicacid
98%
science Other reagents with same CAS 1210834-55-1
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description Product Description
Widely used in peptide synthesis, this compound serves as a chiral building block for introducing N-methyl-protected amino acids with high stereochemical purity. Its Fmoc group provides mild, base-labile protection on the nitrogen, which is also methylated, ideal for solid-phase peptide synthesis (Fmoc-SPPS). This allows stepwise assembly of complex peptides without racemization, while the N-methylation restricts backbone flexibility, enhancing peptide stability against enzymatic degradation and promoting specific conformations. The cyclohexyl side chain imparts hydrophobic character, making it valuable for designing peptides with improved membrane permeability, solubility profiles, or targeted folding patterns. It is particularly useful in the preparation of bioactive peptides, peptidomimetics, pharmaceutical intermediates, and non-proteinogenic amino acid derivatives where stereochemistry, side-chain stability, and modified amide bonds are critical.
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