(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-cyclohexylpropanoicacid

98%

Reagent Code: #232003
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CAS Number 1210834-55-1

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blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 407.50 g/mol
Formula C₂₅H₂₉NO₄
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MDL Number MFCD00156556
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Widely used in peptide synthesis, this compound serves as a chiral building block for introducing N-methyl-protected amino acids with high stereochemical purity. Its Fmoc group provides mild, base-labile protection on the nitrogen, which is also methylated, ideal for solid-phase peptide synthesis (Fmoc-SPPS). This allows stepwise assembly of complex peptides without racemization, while the N-methylation restricts backbone flexibility, enhancing peptide stability against enzymatic degradation and promoting specific conformations. The cyclohexyl side chain imparts hydrophobic character, making it valuable for designing peptides with improved membrane permeability, solubility profiles, or targeted folding patterns. It is particularly useful in the preparation of bioactive peptides, peptidomimetics, pharmaceutical intermediates, and non-proteinogenic amino acid derivatives where stereochemistry, side-chain stability, and modified amide bonds are critical.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿8,340.00
(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-cyclohexylpropanoicacid
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Widely used in peptide synthesis, this compound serves as a chiral building block for introducing N-methyl-protected amino acids with high stereochemical purity. Its Fmoc group provides mild, base-labile protection on the nitrogen, which is also methylated, ideal for solid-phase peptide synthesis (Fmoc-SPPS). This allows stepwise assembly of complex peptides without racemization, while the N-methylation restricts backbone flexibility, enhancing peptide stability against enzymatic degradation and promotin

Widely used in peptide synthesis, this compound serves as a chiral building block for introducing N-methyl-protected amino acids with high stereochemical purity. Its Fmoc group provides mild, base-labile protection on the nitrogen, which is also methylated, ideal for solid-phase peptide synthesis (Fmoc-SPPS). This allows stepwise assembly of complex peptides without racemization, while the N-methylation restricts backbone flexibility, enhancing peptide stability against enzymatic degradation and promoting specific conformations. The cyclohexyl side chain imparts hydrophobic character, making it valuable for designing peptides with improved membrane permeability, solubility profiles, or targeted folding patterns. It is particularly useful in the preparation of bioactive peptides, peptidomimetics, pharmaceutical intermediates, and non-proteinogenic amino acid derivatives where stereochemistry, side-chain stability, and modified amide bonds are critical.

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