(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

98%

Reagent Code: #232190
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CAS Number 274693-49-1

science Other reagents with same CAS 274693-49-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 518.58 g/mol
Formula C₂₄H₂₈F₂N₆O₃S
badge Registry Numbers
MDL Number MFCD26961000
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

This compound is a stereochemically defined intermediate used in the synthesis of Ticagrelor, a potent and reversible P2Y12 receptor antagonist approved as an antiplatelet agent. Ticagrelor is indicated for reducing the risk of thrombotic cardiovascular events in patients with acute coronary syndrome or a history of myocardial infarction. The tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol moiety acts as a protecting group for the vicinal diol during multi-step organic synthesis, preserving the (3aR,4S,6R,6aS) configuration essential for the biological activity of the final API. This intermediate enables efficient production of the drug with high purity and yield, contributing to its role in cardiovascular therapeutics.

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Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿117,000.00
(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
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This compound is a stereochemically defined intermediate used in the synthesis of Ticagrelor, a potent and reversible P2Y12 receptor antagonist approved as an antiplatelet agent. Ticagrelor is indicated for reducing the risk of thrombotic cardiovascular events in patients with acute coronary syndrome or a history of myocardial infarction. The tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol moiety acts as a protecting group for the vicinal diol during multi-step organic synthesis, preserv

This compound is a stereochemically defined intermediate used in the synthesis of Ticagrelor, a potent and reversible P2Y12 receptor antagonist approved as an antiplatelet agent. Ticagrelor is indicated for reducing the risk of thrombotic cardiovascular events in patients with acute coronary syndrome or a history of myocardial infarction. The tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol moiety acts as a protecting group for the vicinal diol during multi-step organic synthesis, preserving the (3aR,4S,6R,6aS) configuration essential for the biological activity of the final API. This intermediate enables efficient production of the drug with high purity and yield, contributing to its role in cardiovascular therapeutics.

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