(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
98%
science Other reagents with same CAS 274693-49-1
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description Product Description
This compound is a stereochemically defined intermediate used in the synthesis of Ticagrelor, a potent and reversible P2Y12 receptor antagonist approved as an antiplatelet agent. Ticagrelor is indicated for reducing the risk of thrombotic cardiovascular events in patients with acute coronary syndrome or a history of myocardial infarction. The tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol moiety acts as a protecting group for the vicinal diol during multi-step organic synthesis, preserving the (3aR,4S,6R,6aS) configuration essential for the biological activity of the final API. This intermediate enables efficient production of the drug with high purity and yield, contributing to its role in cardiovascular therapeutics.
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