(R)-2-(Benzo[b]thiophen-2-yl)-4-benzyl-4,5-dihydrooxazole
97%
science Other reagents with same CAS 2757084-02-7
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description Product Description
Used as a chiral auxiliary in asymmetric synthesis, particularly in the preparation of enantiomerically pure compounds. Its rigid oxazole ring and stereogenic center enable high stereocontrol during carbon-carbon bond-forming reactions. Commonly employed in pharmaceutical synthesis to induce chirality in intermediates, especially in the development of active pharmaceutical ingredients (APIs) where specific enantiomers are required for biological activity. The benzo[b]thiophene group enhances stability and can improve substrate binding in catalytic processes. Often utilized in cyclization and alkylation reactions due to its ability to direct facial selectivity. After serving its purpose, it can be cleaved under mild conditions, leaving the desired chiral product intact.
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