(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl acrylate

≥95%

Reagent Code: #232391
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CAS Number 2244619-11-0

science Other reagents with same CAS 2244619-11-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 512.56 g/mol
Formula C₂₈H₂₈N₆O₄
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in pharmaceutical research as a covalent inhibitor targeting Bruton's tyrosine kinase (BTK), particularly in the development of treatments for autoimmune diseases and certain B-cell malignancies. Its acrylate group enables irreversible binding to cysteine residues in BTK, enhancing prolonged inhibition. The compound is investigated for its potential in overcoming resistance mutations seen with reversible inhibitors. It serves as a key intermediate in synthesizing targeted therapies with improved selectivity and pharmacokinetic profiles.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿34,200.00
(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl acrylate
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Used in pharmaceutical research as a covalent inhibitor targeting Bruton's tyrosine kinase (BTK), particularly in the development of treatments for autoimmune diseases and certain B-cell malignancies. Its acrylate group enables irreversible binding to cysteine residues in BTK, enhancing prolonged inhibition. The compound is investigated for its potential in overcoming resistance mutations seen with reversible inhibitors. It serves as a key intermediate in synthesizing targeted therapies with improved sel

Used in pharmaceutical research as a covalent inhibitor targeting Bruton's tyrosine kinase (BTK), particularly in the development of treatments for autoimmune diseases and certain B-cell malignancies. Its acrylate group enables irreversible binding to cysteine residues in BTK, enhancing prolonged inhibition. The compound is investigated for its potential in overcoming resistance mutations seen with reversible inhibitors. It serves as a key intermediate in synthesizing targeted therapies with improved selectivity and pharmacokinetic profiles.

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