(2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-cyclohexylpyrrolidine-2-carboxylic acid

97%

Reagent Code: #232477
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CAS Number 1820571-03-6

science Other reagents with same CAS 1820571-03-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 419.51 g/mol
Formula C₂₆H₂₉NO₄
badge Registry Numbers
MDL Number MFCD26793611
thermostat Physical Properties
Boiling Point 608.7±48.0 °C(Predicted)
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Widely used in peptide synthesis and medicinal chemistry, this compound serves as a chiral building block for the development of protease inhibitors and other biologically active molecules. Its structure incorporates both a fluorenylmethyloxycarbonyl (Fmoc) protecting group and a sterically defined pyrrolidine scaffold, making it valuable in solid-phase peptide synthesis. The presence of the cyclohexyl substituent enhances lipophilicity and influences conformational rigidity, which can improve binding selectivity and metabolic stability in drug design. It is particularly useful in the synthesis of enzyme inhibitors where stereochemistry plays a critical role in activity. Additionally, its Fmoc group allows for mild deprotection conditions, compatible with a wide range of functional groups, facilitating its use in multi-step syntheses of complex pharmaceuticals.

Available Sizes & Pricing

Size Availability Unit Price Quantity
100mg
10-20 days ฿32,240.00
1g
10-20 days ฿147,880.00
250mg
10-20 days ฿54,790.00
(2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-cyclohexylpyrrolidine-2-carboxylic acid
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Widely used in peptide synthesis and medicinal chemistry, this compound serves as a chiral building block for the development of protease inhibitors and other biologically active molecules. Its structure incorporates both a fluorenylmethyloxycarbonyl (Fmoc) protecting group and a sterically defined pyrrolidine scaffold, making it valuable in solid-phase peptide synthesis. The presence of the cyclohexyl substituent enhances lipophilicity and influences conformational rigidity, which can improve binding selec
Widely used in peptide synthesis and medicinal chemistry, this compound serves as a chiral building block for the development of protease inhibitors and other biologically active molecules. Its structure incorporates both a fluorenylmethyloxycarbonyl (Fmoc) protecting group and a sterically defined pyrrolidine scaffold, making it valuable in solid-phase peptide synthesis. The presence of the cyclohexyl substituent enhances lipophilicity and influences conformational rigidity, which can improve binding selectivity and metabolic stability in drug design. It is particularly useful in the synthesis of enzyme inhibitors where stereochemistry plays a critical role in activity. Additionally, its Fmoc group allows for mild deprotection conditions, compatible with a wide range of functional groups, facilitating its use in multi-step syntheses of complex pharmaceuticals.
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