(2S,4R)-N-(2-(2-(2-(2-((6-Chlorohexyl)oxy)ethoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide

95%

Reagent Code: #233359
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CAS Number 2365478-58-4

science Other reagents with same CAS 2365478-58-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 790.41 g/mol
Formula C₃₉H₅₆ClN₅O₈S
badge Registry Numbers
MDL Number MFCD32662642
thermostat Physical Properties
Boiling Point 983.9±65.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.27±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used in pharmaceutical research as a targeted protein degrader, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structure enables selective binding to specific disease-related proteins, facilitating their degradation via the cell’s ubiquitin-proteasome system. This makes it valuable in oncology and inflammatory disease research, where modulating protein levels is critical. The compound's polyether chain enhances solubility and cellular permeability, improving bioavailability in cellular assays. Its cyanocyclopropane and thiazole components contribute to binding affinity and metabolic stability, supporting use in preclinical studies for optimizing degrader therapeutics.

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Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿16,600.00
(2S,4R)-N-(2-(2-(2-(2-((6-Chlorohexyl)oxy)ethoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide
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Used in pharmaceutical research as a targeted protein degrader, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structure enables selective binding to specific disease-related proteins, facilitating their degradation via the cell’s ubiquitin-proteasome system. This makes it valuable in oncology and inflammatory disease research, where modulating protein levels is critical. The compound's polyether chain enhances solubility and cellular permeability, improving bioavailabil

Used in pharmaceutical research as a targeted protein degrader, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structure enables selective binding to specific disease-related proteins, facilitating their degradation via the cell’s ubiquitin-proteasome system. This makes it valuable in oncology and inflammatory disease research, where modulating protein levels is critical. The compound's polyether chain enhances solubility and cellular permeability, improving bioavailability in cellular assays. Its cyanocyclopropane and thiazole components contribute to binding affinity and metabolic stability, supporting use in preclinical studies for optimizing degrader therapeutics.

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