(S)-tert-Butyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)pyrrolidine-1-carboxylate
≥95%
science Other reagents with same CAS 1417789-41-3
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for targeted cancer therapies. The tert-butyl carbamate moiety acts as a protecting group for the pyrrolidine nitrogen, enabling selective functionalization and control over reaction pathways, which can be deprotected in later stages. Its chiral (S) configuration enables selective interactions with biological targets, enhancing drug efficacy and reducing off-target effects. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the stability and modifiability of the pyrrolidine and pyridine moieties. Also utilized in the preparation of protease inhibitors and anti-inflammatory compounds. The presence of trifluoromethyl and chloro groups improves metabolic stability and membrane permeability, making it valuable in optimizing pharmacokinetic properties of drug candidates.
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