(S)-tert-Butyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)pyrrolidine-1-carboxylate

≥95%

Reagent Code: #233409
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CAS Number 1417789-41-3

science Other reagents with same CAS 1417789-41-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 366.76 g/mol
Formula C₁₅H₁₈ClF₃N₂O₃
badge Registry Numbers
MDL Number MFCD22631739
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for targeted cancer therapies. The tert-butyl carbamate moiety acts as a protecting group for the pyrrolidine nitrogen, enabling selective functionalization and control over reaction pathways, which can be deprotected in later stages. Its chiral (S) configuration enables selective interactions with biological targets, enhancing drug efficacy and reducing off-target effects. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the stability and modifiability of the pyrrolidine and pyridine moieties. Also utilized in the preparation of protease inhibitors and anti-inflammatory compounds. The presence of trifluoromethyl and chloro groups improves metabolic stability and membrane permeability, making it valuable in optimizing pharmacokinetic properties of drug candidates.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿12,400.00
inventory 1g
10-20 days ฿33,500.00
(S)-tert-Butyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)pyrrolidine-1-carboxylate
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Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for targeted cancer therapies. The tert-butyl carbamate moiety acts as a protecting group for the pyrrolidine nitrogen, enabling selective functionalization and control over reaction pathways, which can be deprotected in later stages. Its chiral (S) configuration enables selective interactions with biological targets, enhancing drug efficacy and reducing off-target effects. Commonly

Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for targeted cancer therapies. The tert-butyl carbamate moiety acts as a protecting group for the pyrrolidine nitrogen, enabling selective functionalization and control over reaction pathways, which can be deprotected in later stages. Its chiral (S) configuration enables selective interactions with biological targets, enhancing drug efficacy and reducing off-target effects. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the stability and modifiability of the pyrrolidine and pyridine moieties. Also utilized in the preparation of protease inhibitors and anti-inflammatory compounds. The presence of trifluoromethyl and chloro groups improves metabolic stability and membrane permeability, making it valuable in optimizing pharmacokinetic properties of drug candidates.

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