(S)-2-(2,6-Dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

95%

Reagent Code: #233473
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CAS Number 2357105-36-1

science Other reagents with same CAS 2357105-36-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 274.23 g/mol
Formula C₁₃H₁₀N₂O₅
thermostat Physical Properties
Boiling Point 568.3±45.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.611±0.06 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used primarily in the pharmaceutical industry as an active pharmaceutical ingredient (API) intermediate for synthesizing immunomodulatory drugs. It plays a critical role in the production of targeted protein degraders, such as cereblon E3 ligase modulators, which are employed in the treatment of certain cancers, including multiple myeloma and myelodysplastic syndromes. Its structure enables selective binding to cereblon, facilitating the degradation of disease-causing proteins. Due to its chiral center, the (S)-enantiomer exhibits higher biological activity and specificity compared to the racemic form, making it essential for developing potent and safer therapeutics. Also utilized in research settings for developing novel degrader molecules and studying ubiquitin-proteasome pathways.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿12,200.00
inventory 250mg
10-20 days ฿21,960.00
(S)-2-(2,6-Dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione
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Used primarily in the pharmaceutical industry as an active pharmaceutical ingredient (API) intermediate for synthesizing immunomodulatory drugs. It plays a critical role in the production of targeted protein degraders, such as cereblon E3 ligase modulators, which are employed in the treatment of certain cancers, including multiple myeloma and myelodysplastic syndromes. Its structure enables selective binding to cereblon, facilitating the degradation of disease-causing proteins. Due to its chiral center,

Used primarily in the pharmaceutical industry as an active pharmaceutical ingredient (API) intermediate for synthesizing immunomodulatory drugs. It plays a critical role in the production of targeted protein degraders, such as cereblon E3 ligase modulators, which are employed in the treatment of certain cancers, including multiple myeloma and myelodysplastic syndromes. Its structure enables selective binding to cereblon, facilitating the degradation of disease-causing proteins. Due to its chiral center, the (S)-enantiomer exhibits higher biological activity and specificity compared to the racemic form, making it essential for developing potent and safer therapeutics. Also utilized in research settings for developing novel degrader molecules and studying ubiquitin-proteasome pathways.

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