Used in research for treating hair loss, particularly androgenetic alopecia. It works by blocking the prostaglandin D2 receptor (DP1), which is involved in the miniaturization of hair follicles. Elevated levels of prostaglandin D2 have been found in the scalps of individuals with pattern hair loss, making setipiprant a potential therapeutic agent to promote hair regrowth. It has been investigated as a topical and oral treatment in clinical trials, showing promise in increasing hair count without the hormonal side effects associated with other treatments like minoxidil or finasteride. Also explored for asthma and allergic conditions due to its anti-inflammatory properties, though development in those areas has been limited.