Sivelestat sodium
10mM in DMSO
Reagent
Code: #234129
CAS Number
201677-61-4
science Other reagents with same CAS 201677-61-4
blur_circular Chemical Specifications
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Molecular Information
Weight
528.51 g/mol
Formula
C₂₀H₂₁N₂O₇S·₄H₂O·Na
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Registry Numbers
MDL Number
MFCD01937969
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the management of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), especially associated with systemic inflammatory response. It functions by inhibiting neutrophil elastase, an enzyme that contributes to lung tissue damage during severe inflammation. By blocking this enzyme, it helps reduce pulmonary inflammation and capillary leakage, improving oxygenation and lung function. Commonly administered intravenously in critical care settings, particularly in patients with sepsis-induced ARDS. Its use is aimed at shortening the duration of mechanical ventilation and supporting recovery in intensive care units.
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