Sulfuretin is widely used in the cosmetic and skincare industry due to its strong antioxidant properties. It helps protect the skin from oxidative stress and environmental damage, making it effective in anti-aging formulations by reducing wrinkles and fading freckles. It is commonly incorporated into moisturizing creams, sunscreens, and serums to restore sun-damaged skin. It is also known for its anti-inflammatory effects, which can soothe irritated skin and reduce redness, benefiting sensitive or acne-prone skin types.

In medical research, sulfuretin is studied for its potential to prevent or slow chronic diseases such as diabetes, Alzheimer's disease, and cancer, by inhibiting signaling pathways involved in chronic inflammation and abnormal cell death.

In addition to skincare, sulfuretin shows potential in functional foods, dietary supplements, and the food industry as a natural preservative and coloring agent, providing safe yellow to orange hues. It supports metabolic health by helping regulate blood sugar levels and improve insulin sensitivity, indicating applications in managing diabetes and metabolic syndrome.

It is also used in natural dye applications for textiles and food products, serving as a safer alternative to synthetic dyes. Its biodegradability and low toxicity make it suitable for eco-friendly and sustainable product development.