(2S,4R)-1-tert-butyl 2-methyl 4-((tert-butyldiphenylsilyl)oxy)pyrrolidine-1,2-dicarboxylate
95%
Reagent
Code: #236250
CAS Number
226225-42-9
science Other reagents with same CAS 226225-42-9
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Molecular Information
Weight
483.68 g/mol
Formula
C₂₇H₃₇NO₅Si
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a chiral building block in the synthesis of complex pharmaceuticals, particularly in the development of protease inhibitors. Its protected hydroxyl and carboxyl groups allow selective reactions in multi-step organic syntheses. The silyl ether group provides stability under various reaction conditions and can be removed selectively to reveal the alcohol functionality when needed. Commonly employed in asymmetric synthesis due to the defined stereochemistry at the 2 and 4 positions of the pyrrolidine ring, making it valuable for constructing stereochemically complex drug molecules.
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