(2S,4R)-1-tert-butyl 2-methyl 4-((tert-butyldiphenylsilyl)oxy)pyrrolidine-1,2-dicarboxylate

95%

Reagent Code: #236250
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CAS Number 226225-42-9

science Other reagents with same CAS 226225-42-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 483.68 g/mol
Formula C₂₇H₃₇NO₅Si
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as a chiral building block in the synthesis of complex pharmaceuticals, particularly in the development of protease inhibitors. Its protected hydroxyl and carboxyl groups allow selective reactions in multi-step organic syntheses. The silyl ether group provides stability under various reaction conditions and can be removed selectively to reveal the alcohol functionality when needed. Commonly employed in asymmetric synthesis due to the defined stereochemistry at the 2 and 4 positions of the pyrrolidine ring, making it valuable for constructing stereochemically complex drug molecules.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,190.00
inventory 250mg
10-20 days ฿3,900.00
inventory 1g
10-20 days ฿10,500.00
(2S,4R)-1-tert-butyl 2-methyl 4-((tert-butyldiphenylsilyl)oxy)pyrrolidine-1,2-dicarboxylate
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Used as a chiral building block in the synthesis of complex pharmaceuticals, particularly in the development of protease inhibitors. Its protected hydroxyl and carboxyl groups allow selective reactions in multi-step organic syntheses. The silyl ether group provides stability under various reaction conditions and can be removed selectively to reveal the alcohol functionality when needed. Commonly employed in asymmetric synthesis due to the defined stereochemistry at the 2 and 4 positions of the pyrrolidine ring, making it valuable for constructing stereochemically complex drug molecules.
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