(S)-2-Amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one 2,2,2-trifluoroacetate
95%
science Other reagents with same CAS 247068-85-5
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Used as a key intermediate in the synthesis of protease inhibitors, particularly in the development of antiviral drugs. Its chiral structure, featuring an epoxide ring sensitive to nucleophilic ring-opening, an amino group, and a ketone functionality, enables selective interactions with enzyme active sites and facilitates conjugation with peptides or heterocyclic compounds. This makes it valuable in pharmaceutical research for designing inhibitors with high specificity and potency. Commonly employed in the preparation of renin and HIV protease inhibitors due to its ability to mimic peptide transition states. Also utilized in asymmetric synthesis where stereochemical control is critical for biological activity.
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