(S)-1-(4-bromo-2-fluorophenyl)ethan-1-amine
95%
Reagent
Code: #236611
CAS Number
1228559-00-9
science Other reagents with same CAS 1228559-00-9
blur_circular Chemical Specifications
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Molecular Information
Weight
218.07 g/mol
Formula
C₈H₉BrFN
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Registry Numbers
MDL Number
MFCD07772674
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Physical Properties
Boiling Point
250.1±25.0 °C(Predicted)
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Storage & Handling
Density
1.482±0.06 g/cm3(Predicted)
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as a chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where stereochemistry plays a critical role in biological activity. Its structure contains both bromo and fluoro substituents, making it valuable for further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in the preparation of neuroactive compounds and receptor modulators due to the aromatic halogen pattern influencing target binding affinity. The presence of the primary amine group allows for amide bond formation or reductive amination, enabling integration into larger molecular architectures. Frequently utilized in medicinal chemistry research for structure-activity relationship (SAR) studies.
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