(S)-1-(4-bromo-2-fluorophenyl)ethan-1-amine

95%

Reagent Code: #236611
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CAS Number 1228559-00-9

science Other reagents with same CAS 1228559-00-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 218.07 g/mol
Formula C₈H₉BrFN
badge Registry Numbers
MDL Number MFCD07772674
thermostat Physical Properties
Boiling Point 250.1±25.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.482±0.06 g/cm3(Predicted)
Storage Room temperature, light-proof, inert gas

description Product Description

Used as a chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where stereochemistry plays a critical role in biological activity. Its structure contains both bromo and fluoro substituents, making it valuable for further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in the preparation of neuroactive compounds and receptor modulators due to the aromatic halogen pattern influencing target binding affinity. The presence of the primary amine group allows for amide bond formation or reductive amination, enabling integration into larger molecular architectures. Frequently utilized in medicinal chemistry research for structure-activity relationship (SAR) studies.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿12,400.00
inventory 1g
10-20 days ฿50,060.00
inventory 250mg
10-20 days ฿18,540.00
(S)-1-(4-bromo-2-fluorophenyl)ethan-1-amine
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Used as a chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where stereochemistry plays a critical role in biological activity. Its structure contains both bromo and fluoro substituents, making it valuable for further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Commonly employed in the preparation of neuroactive compounds and receptor modulators due to the aromatic halogen pattern influencing target binding affinity. The presence of the primary amine group allows for amide bond formation or reductive amination, enabling integration into larger molecular architectures. Frequently utilized in medicinal chemistry research for structure-activity relationship (SAR) studies.
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