SR 11237 is primarily used in research settings as a selective modulator of retinoid receptors, particularly the retinoid X receptor (RXR). Its main application lies in the study of cellular differentiation, lipid metabolism, and glucose homeostasis. Due to its ability to influence gene expression involved in metabolic pathways, it has been investigated for potential therapeutic roles in metabolic disorders such as type 2 diabetes and dyslipidemia. It is also employed in cancer research, where RXR modulation can induce apoptosis and inhibit proliferation in certain tumor cell lines. Its use remains largely confined to preclinical studies, serving as a tool compound to dissect RXR-mediated signaling pathways.