(2S,4R)-3-tert-Butyl 4-methyl 2-tert-butyloxazolidine-3,4-dicarboxylate
97%
science Other reagents with same CAS 380429-42-5
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description Product Description
Used as a chiral auxiliary in asymmetric synthesis, enabling high stereoselectivity in carbon-carbon bond-forming reactions. It is particularly effective in enolate alkylations and aldol reactions, where it controls the formation of new stereocenters. The rigid oxazolidine ring and bulky tert-butyl groups shield one face of the molecule, directing reagent approach to the opposite face. After the desired transformation, the auxiliary can be cleaved under mild conditions to yield enantiomerically enriched carboxylic acids, alcohols, or other functionalized products. Widely employed in the synthesis of complex natural products and pharmaceutical intermediates.
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