Used as a key chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents. Its fluorinated chroman structure with an amine functional group enables enhanced binding selectivity and metabolic stability in drug candidates. Commonly employed in the preparation of serotonin and dopamine receptor modulators for treating neurological disorders such as depression, anxiety, and Parkinson’s disease. The (S)-enantiomer’s stereochemistry is critical for biological activity, making it valuable in asymmetric synthesis routes for active pharmaceutical ingredients (APIs).