(8S)-1,6,7,8-Tetrahydro-2-[(3R)-3-Methyl-4-Morpholinyl]-8-(Trifluoromethyl)-4H-Pyrimido[1,2-A]Pyrimidin-4-One

96%

Reagent Code: #237280
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CAS Number 1523412-59-0

science Other reagents with same CAS 1523412-59-0

blur_circular Chemical Specifications

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Weight 318.29 g/mol
Formula C₁₃H₁₇F₃N₄O₂
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), this compound is investigated for its potential in treating central nervous system disorders, particularly schizophrenia and other psychiatric conditions involving dysregulation of dopamine signaling. By modulating intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in the brain, it helps regulate neuronal activity in pathways associated with cognition, motivation, and reward. Its ability to cross the blood-brain barrier enhances its utility in neuropharmacology. Preclinical studies focus on its efficacy in improving cognitive and negative symptoms of schizophrenia without inducing motor side effects commonly seen with antipsychotics.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿70,900.00
(8S)-1,6,7,8-Tetrahydro-2-[(3R)-3-Methyl-4-Morpholinyl]-8-(Trifluoromethyl)-4H-Pyrimido[1,2-A]Pyrimidin-4-One
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Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), this compound is investigated for its potential in treating central nervous system disorders, particularly schizophrenia and other psychiatric conditions involving dysregulation of dopamine signaling. By modulating intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in the brain, it helps regulate neuronal activity in pathways associated with cognition

Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), this compound is investigated for its potential in treating central nervous system disorders, particularly schizophrenia and other psychiatric conditions involving dysregulation of dopamine signaling. By modulating intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in the brain, it helps regulate neuronal activity in pathways associated with cognition, motivation, and reward. Its ability to cross the blood-brain barrier enhances its utility in neuropharmacology. Preclinical studies focus on its efficacy in improving cognitive and negative symptoms of schizophrenia without inducing motor side effects commonly seen with antipsychotics.

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