(2S,4R)-1-(Tert-Butoxycarbonyl)-4-(Trifluoromethyl)Pyrrolidine-2-Carboxylic Acid
97%
science Other reagents with same CAS 470482-44-1
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description Product Description
Used as a chiral building block in the synthesis of pharmaceuticals, particularly in the development of protease inhibitors and other bioactive molecules. Its rigid pyrrolidine structure with defined stereochemistry enhances selectivity and binding affinity in drug candidates. The tert-butoxycarbonyl (Boc) group allows for easy protection and deprotection during peptide coupling or multistep synthesis. The trifluoromethyl substituent improves metabolic stability and lipophilicity, making it valuable in optimizing pharmacokinetic properties. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies and in the preparation of small-molecule therapeutics targeting viral infections, cancer, and central nervous system disorders.
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