(2S,4R)-1-(Tert-Butoxycarbonyl)-4-(Trifluoromethyl)Pyrrolidine-2-Carboxylic Acid

97%

Reagent Code: #237329
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CAS Number 470482-44-1

science Other reagents with same CAS 470482-44-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 283.24 g/mol
Formula C₁₁H₁₆F₃NO₄
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as a chiral building block in the synthesis of pharmaceuticals, particularly in the development of protease inhibitors and other bioactive molecules. Its rigid pyrrolidine structure with defined stereochemistry enhances selectivity and binding affinity in drug candidates. The tert-butoxycarbonyl (Boc) group allows for easy protection and deprotection during peptide coupling or multistep synthesis. The trifluoromethyl substituent improves metabolic stability and lipophilicity, making it valuable in optimizing pharmacokinetic properties. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies and in the preparation of small-molecule therapeutics targeting viral infections, cancer, and central nervous system disorders.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿10,100.00
inventory 250mg
10-20 days ฿16,160.00
inventory 1g
10-20 days ฿44,450.00
(2S,4R)-1-(Tert-Butoxycarbonyl)-4-(Trifluoromethyl)Pyrrolidine-2-Carboxylic Acid
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Used as a chiral building block in the synthesis of pharmaceuticals, particularly in the development of protease inhibitors and other bioactive molecules. Its rigid pyrrolidine structure with defined stereochemistry enhances selectivity and binding affinity in drug candidates. The tert-butoxycarbonyl (Boc) group allows for easy protection and deprotection during peptide coupling or multistep synthesis. The trifluoromethyl substituent improves metabolic stability and lipophilicity, making it valuable in o

Used as a chiral building block in the synthesis of pharmaceuticals, particularly in the development of protease inhibitors and other bioactive molecules. Its rigid pyrrolidine structure with defined stereochemistry enhances selectivity and binding affinity in drug candidates. The tert-butoxycarbonyl (Boc) group allows for easy protection and deprotection during peptide coupling or multistep synthesis. The trifluoromethyl substituent improves metabolic stability and lipophilicity, making it valuable in optimizing pharmacokinetic properties. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies and in the preparation of small-molecule therapeutics targeting viral infections, cancer, and central nervous system disorders.

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