Used as a crosslinking agent in bioconjugation, particularly for coupling proteins or peptides to surfaces or other biomolecules. Its sulfo group enhances water solubility, making it suitable for reactions in aqueous environments. Commonly applied in the development of immunoassays, biosensors, and targeted drug delivery systems where stable linkage between biomolecules is required. Also utilized in proteomics research for protein immobilization on solid supports, enabling studies of protein interactions and functions.