(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate

95%

Reagent Code: #237978
fingerprint
CAS Number 215918-21-1

science Other reagents with same CAS 215918-21-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 237.24 g/mol
Formula C₁₀H₁₇F₂NO₃
badge Registry Numbers
MDL Number MFCD12755205
thermostat Physical Properties
Boiling Point 293.4±40.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.21±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of fluorinated analogs of bioactive molecules. Its structure supports conformational rigidity and enhanced metabolic stability, making it valuable in medicinal chemistry for optimizing drug candidates. Commonly employed in the preparation of protease inhibitors and central nervous system-targeted compounds due to its ability to improve blood-brain barrier penetration. The presence of the hydroxymethyl group allows for further functionalization, enabling linkage to other pharmacophores or prodrug modifications. Widely utilized in asymmetric synthesis routes where stereochemical control is critical for biological activity.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿5,400.00
inventory 1g
10-20 days ฿14,560.00
inventory 5g
10-20 days ฿53,480.00
(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate
No image available

Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of fluorinated analogs of bioactive molecules. Its structure supports conformational rigidity and enhanced metabolic stability, making it valuable in medicinal chemistry for optimizing drug candidates. Commonly employed in the preparation of protease inhibitors and central nervous system-targeted compounds due to its ability to improve blood-brain barrier penetration. The presence of the hydroxyme

Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of fluorinated analogs of bioactive molecules. Its structure supports conformational rigidity and enhanced metabolic stability, making it valuable in medicinal chemistry for optimizing drug candidates. Commonly employed in the preparation of protease inhibitors and central nervous system-targeted compounds due to its ability to improve blood-brain barrier penetration. The presence of the hydroxymethyl group allows for further functionalization, enabling linkage to other pharmacophores or prodrug modifications. Widely utilized in asymmetric synthesis routes where stereochemical control is critical for biological activity.

Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Purchase History for

Loading purchase history...