Tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)((2-(trimethylsilyl)ethoxy)methyl)carbamate
98%
Reagent
Code: #238173
CAS Number
1228356-82-8
science Other reagents with same CAS 1228356-82-8
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Molecular Information
Weight
456.48 g/mol
Formula
C₂₀H₃₇BN₂O₅SSi
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Storage & Handling
Storage
-20°C, Inert Gas
description Product Description
Used primarily as an intermediate in the synthesis of pharmaceutical compounds, this chemical plays a key role in Suzuki-Miyaura cross-coupling reactions due to the presence of the boronate ester group. The thiazole ring serves as a common scaffold in bioactive molecules, making this compound valuable in drug discovery. The SEM (2-(trimethylsilyl)ethoxy)methyl protecting group ensures selective amine protection during multi-step syntheses, allowing controlled deprotection under mild conditions. Its main application is in the development of heterocyclic drugs, especially in oncology and antiviral research, where precise molecular construction is critical.
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