Used in veterinary medicine to treat respiratory diseases in cattle and swine caused by susceptible strains of bacteria such as Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. It is effective in controlling bovine respiratory disease (BRD) in beef and dairy cattle, including cases with known risk factors like stress or weaning. In swine, it treats swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, and Haemophilus parasuis. Administered as a single injection, it provides long-lasting therapeutic levels due to its extended half-life, reducing the need for repeated dosing and improving animal welfare and farm efficiency.