2-(Trifluoromethyl)pyridin-4-ol
95%
science Other reagents with same CAS 170886-13-2
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and antiviral agents. Its structure supports the design of bioactive molecules due to the electron-withdrawing trifluoromethyl group and the hydrogen-bonding capability of the hydroxyl group. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to enhance metabolic stability and binding affinity. Also utilized in agrochemicals for the development of herbicides and fungicides owing to its ability to improve lipophilicity and environmental persistence. Frequently incorporated into ligands for catalysis, especially in transition metal-catalyzed cross-coupling reactions.