4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane
97%
Reagent
Code: #240916
CAS Number
475250-46-5
science Other reagents with same CAS 475250-46-5
blur_circular Chemical Specifications
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Molecular Information
Weight
286.1 g/mol
Formula
C₁₄H₁₈BF₃O₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boron-containing structure acts as a stable organoboron precursor, facilitating coupling with aryl halides under palladium catalysis. Particularly valuable for introducing trifluoromethyl-substituted aryl groups into complex molecules, enhancing metabolic stability and lipophilicity in drug design. Also employed in materials science for constructing conjugated organic frameworks and functionalized aromatic systems.