4,4,4-Trifluorobutanal
96%
science Other reagents with same CAS 406-87-1
blur_circular Chemical Specifications
description Product Description
Used primarily as an intermediate in organic synthesis, especially in the pharmaceutical and agrochemical industries. Its electrophilic aldehyde group and electron-withdrawing trifluoromethyl moiety make it valuable for constructing fluorinated compounds, which often exhibit enhanced metabolic stability and bioavailability. Commonly employed in aldol condensations, reductive aminations, and nucleophilic additions to introduce the CF3-containing butyl chain into larger molecules. Also utilized in the preparation of fluorinated analogs of natural products and bioactive molecules, where the trifluoromethyl group can mimic metabolic resistance or alter lipophilicity. Its reactivity allows for selective transformations under mild conditions, making it suitable for complex molecule assembly.