4-trifluoromethylbenzeneboronic acid neopentyl glycol ester

98%

Reagent Code: #241563
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CAS Number 501374-30-7

science Other reagents with same CAS 501374-30-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 258.04 g/mol
Formula C₁₂H₁₄BF₃O₂
inventory_2 Storage & Handling
Storage 2-8℃, dry, sealed

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronic ester structure offers improved stability and handling compared to the corresponding boronic acid, making it suitable for large-scale applications. Commonly employed in the preparation of biaryl compounds, especially in drug discovery where the trifluoromethyl group enhances metabolic stability and lipophilicity. The neopentyl glycol ester moiety facilitates purification and enhances crystallinity, beneficial in solid-phase synthesis and high-throughput screening.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿720.00
inventory 5g
10-20 days ฿2,500.00
4-trifluoromethylbenzeneboronic acid neopentyl glycol ester
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Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronic ester structure offers improved stability and handling compared to the corresponding boronic acid, making it suitable for large-scale applications. Commonly employed in the preparation of biaryl compounds, especially in drug discovery where the trifluoromethyl group enhances metabolic stability and lipophilicity. The neopentyl glyco

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronic ester structure offers improved stability and handling compared to the corresponding boronic acid, making it suitable for large-scale applications. Commonly employed in the preparation of biaryl compounds, especially in drug discovery where the trifluoromethyl group enhances metabolic stability and lipophilicity. The neopentyl glycol ester moiety facilitates purification and enhances crystallinity, beneficial in solid-phase synthesis and high-throughput screening.

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