4-trifluoromethylbenzeneboronic acid neopentyl glycol ester
98%
science Other reagents with same CAS 501374-30-7
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronic ester structure offers improved stability and handling compared to the corresponding boronic acid, making it suitable for large-scale applications. Commonly employed in the preparation of biaryl compounds, especially in drug discovery where the trifluoromethyl group enhances metabolic stability and lipophilicity. The neopentyl glycol ester moiety facilitates purification and enhances crystallinity, beneficial in solid-phase synthesis and high-throughput screening.