(4-(Trifluoromethyl)pyridin-2-yl)boronic acid
97%
Reagent
Code: #241660
CAS Number
870459-90-8
science Other reagents with same CAS 870459-90-8
blur_circular Chemical Specifications
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Molecular Information
Weight
190.92 g/mol
Formula
C₆H₅BF₃NO₂
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Registry Numbers
MDL Number
MFCD08063026
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Physical Properties
Boiling Point
316.1±52.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronic acid group enables efficient carbon-carbon bond formation, particularly in the development of bioactive molecules containing trifluoromethylpyridine moieties. The electron-withdrawing trifluoromethyl group enhances metabolic stability and lipophilicity, making this compound valuable in medicinal chemistry for designing drug candidates with improved pharmacokinetic properties. It is also employed in the preparation of functional materials and ligands for catalysis.