2-(2,2,2-Trifluoroethoxy)pyrimidine-5-carboxylic acid
97%
science Other reagents with same CAS 944905-08-2
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and antiviral drugs. Its structure supports binding to enzyme active sites, enhancing biological activity. The trifluoroethoxy group improves metabolic stability and lipophilicity, making it valuable in optimizing drug candidates for better oral bioavailability and target selectivity. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to refine potency and pharmacokinetic properties.