Used in epigenetic research to inhibit the G9a and GLP histone methyltransferases, leading to reduced H3K9me2 levels in cells. This inhibition helps reactivate silenced genes, making it a valuable tool for studying gene expression, chromatin dynamics, and cellular differentiation. Commonly applied in studies related to cancer, stem cell biology, and developmental disorders where epigenetic regulation plays a critical role. Shows potential for enhancing reprogramming efficiency in induced pluripotent stem cell (iPSC) generation. Due to its cell permeability and potency, it is widely used in cellular assays to probe the functional consequences of G9a/GLP inhibition.