VH 032 amide-PEG3-amine dihydrochloride
95%
science Other reagents with same CAS 2376990-24-6
blur_circular Chemical Specifications
description Product Description
Used in bioconjugation processes, particularly in the development of PROTACs (proteolysis targeting chimeras) for targeted protein degradation. The amine functionality allows for coupling to carboxylic acids or other activated groups, while the PEG3 linker provides water solubility and improved pharmacokinetic properties. The VH 032 moiety acts as a ligand for the von Hippel-Lindau (VHL) E3 ubiquitin ligase, enabling recruitment of the cellular degradation machinery. This compound is therefore valuable in medicinal chemistry research for designing molecules that induce degradation of disease-related proteins. Commonly employed in early-stage drug discovery and chemical biology studies to probe protein function and develop novel therapeutics.
shopping_cart Available Sizes & Pricing
Cart
No products