VH 032 amide-PEG3-amine dihydrochloride

95%

Reagent Code: #245190
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CAS Number 2376990-24-6

science Other reagents with same CAS 2376990-24-6

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Weight 692.69 g/mol
Formula C₃₀H₄₅N₅O₇S·₂HCl
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

Used in bioconjugation processes, particularly in the development of PROTACs (proteolysis targeting chimeras) for targeted protein degradation. The amine functionality allows for coupling to carboxylic acids or other activated groups, while the PEG3 linker provides water solubility and improved pharmacokinetic properties. The VH 032 moiety acts as a ligand for the von Hippel-Lindau (VHL) E3 ubiquitin ligase, enabling recruitment of the cellular degradation machinery. This compound is therefore valuable in medicinal chemistry research for designing molecules that induce degradation of disease-related proteins. Commonly employed in early-stage drug discovery and chemical biology studies to probe protein function and develop novel therapeutics.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿6,800.00
inventory 25mg
10-20 days ฿20,290.00

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VH 032 amide-PEG3-amine dihydrochloride
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Used in bioconjugation processes, particularly in the development of PROTACs (proteolysis targeting chimeras) for targeted protein degradation. The amine functionality allows for coupling to carboxylic acids or other activated groups, while the PEG3 linker provides water solubility and improved pharmacokinetic properties. The VH 032 moiety acts as a ligand for the von Hippel-Lindau (VHL) E3 ubiquitin ligase, enabling recruitment of the cellular degradation machinery. This compound is therefore valuable i

Used in bioconjugation processes, particularly in the development of PROTACs (proteolysis targeting chimeras) for targeted protein degradation. The amine functionality allows for coupling to carboxylic acids or other activated groups, while the PEG3 linker provides water solubility and improved pharmacokinetic properties. The VH 032 moiety acts as a ligand for the von Hippel-Lindau (VHL) E3 ubiquitin ligase, enabling recruitment of the cellular degradation machinery. This compound is therefore valuable in medicinal chemistry research for designing molecules that induce degradation of disease-related proteins. Commonly employed in early-stage drug discovery and chemical biology studies to probe protein function and develop novel therapeutics.

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