VH 032 amide-alkylC8-acid
95%
science Other reagents with same CAS 2172819-77-9
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description Product Description
Used in protein degradation research, particularly in PROTAC (Proteolysis Targeting Chimeras) technology. Acts as an E3 ligase ligand that recruits target proteins for ubiquitination and subsequent degradation by the proteasome. Its alkyl chain linker with carboxylic acid functionality allows conjugation to target-binding molecules, enabling the development of heterobifunctional degraders. Commonly applied in the design of novel therapeutics for cancer and other diseases driven by pathological proteins. Suitable for cellular and biochemical assays requiring selective protein knockdown.
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