2-Propen-1-one,1-[4-(4-acetylphenyl)-1-piperazinyl]-3-[1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-,(2E)-
95%
science Other reagents with same CAS 956949-45-4
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description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 4 (PDE4), particularly targeting PDE4B and PDE4D isoforms. It demonstrates anti-inflammatory properties by reducing the production of pro-inflammatory cytokines such as TNF-α and IL-17, making it a candidate for treating autoimmune and inflammatory diseases like rheumatoid arthritis, psoriasis, and chronic obstructive pulmonary disease (COPD). Its structure allows for enhanced blood-brain barrier penetration, which supports investigation in neuroinflammatory conditions. Also employed as a biochemical tool in cellular assays to study cAMP signaling pathways and immune cell regulation.
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