2-Propen-1-one,1-[4-(4-acetylphenyl)-1-piperazinyl]-3-[1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-,(2E)-

95%

Reagent Code: #245615
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CAS Number 956949-45-4

science Other reagents with same CAS 956949-45-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 446.5 g/mol
Formula C₂₆H₂₇FN₄O₂
thermostat Physical Properties
Boiling Point 667.2±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.21±0.1 g/cm3(Predicted)
Storage -20°C, Sealed, Dry

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 4 (PDE4), particularly targeting PDE4B and PDE4D isoforms. It demonstrates anti-inflammatory properties by reducing the production of pro-inflammatory cytokines such as TNF-α and IL-17, making it a candidate for treating autoimmune and inflammatory diseases like rheumatoid arthritis, psoriasis, and chronic obstructive pulmonary disease (COPD). Its structure allows for enhanced blood-brain barrier penetration, which supports investigation in neuroinflammatory conditions. Also employed as a biochemical tool in cellular assays to study cAMP signaling pathways and immune cell regulation.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿9,900.00
inventory 100mg
10-20 days ฿27,500.00

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2-Propen-1-one,1-[4-(4-acetylphenyl)-1-piperazinyl]-3-[1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-,(2E)-
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Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 4 (PDE4), particularly targeting PDE4B and PDE4D isoforms. It demonstrates anti-inflammatory properties by reducing the production of pro-inflammatory cytokines such as TNF-α and IL-17, making it a candidate for treating autoimmune and inflammatory diseases like rheumatoid arthritis, psoriasis, and chronic obstructive pulmonary disease (COPD). Its structure allows for enhanced blood-brain barrier penetration, which s

Used in pharmaceutical research as a potent and selective inhibitor of phosphodiesterase 4 (PDE4), particularly targeting PDE4B and PDE4D isoforms. It demonstrates anti-inflammatory properties by reducing the production of pro-inflammatory cytokines such as TNF-α and IL-17, making it a candidate for treating autoimmune and inflammatory diseases like rheumatoid arthritis, psoriasis, and chronic obstructive pulmonary disease (COPD). Its structure allows for enhanced blood-brain barrier penetration, which supports investigation in neuroinflammatory conditions. Also employed as a biochemical tool in cellular assays to study cAMP signaling pathways and immune cell regulation.

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