8H-1,3-Dioxolo[4,5-g][1]benzopyran-7-carbonitrile, 6-amino-8-(3-bromo-4,5-dimethoxyphenyl)
98%
Reagent
Code: #245808
CAS Number
663214-57-1
science Other reagents with same CAS 663214-57-1
blur_circular Chemical Specifications
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Molecular Information
Weight
431.24 g/mol
Formula
C₁₉H₁₅BrN₂O₅
thermostat
Physical Properties
Boiling Point
563.4±50.0 °C(Predicted)
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Storage & Handling
Density
1.66±0.1 g/cm3(Predicted)
Storage
-20°C, Sealed, Dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of potent kinase inhibitors, particularly targeting PIM kinases involved in cancer cell proliferation. Its structure supports high binding affinity to enzyme active sites, making it valuable in developing antitumor agents. Also explored in the design of anti-inflammatory and neuroprotective compounds due to its ability to cross the blood-brain barrier. Commonly employed in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates.
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