WHI-P97 is primarily used in biomedical research as a selective inhibitor of the Janus kinase 3 (JAK3) signaling pathway. It is valued for its ability to suppress JAK3-mediated cellular processes, making it a tool compound for studying immune cell signaling and inflammation. Researchers apply WHI-P97 to investigate the role of JAK3 in lymphocyte activation and proliferation, particularly in the context of autoimmune diseases and transplant rejection. Due to its specificity, it helps dissect signaling mechanisms without broadly affecting other kinase pathways. It is not used clinically but serves as a prototype for developing targeted immunomodulatory agents.