XE-991 dihydrochloride
10mM in DMSO
Reagent
Code: #246032
CAS Number
122955-13-9
science Other reagents with same CAS 122955-13-9
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Molecular Information
Weight
449.3717 g/mol
Formula
C₂₆H₂₂Cl₂N₂O
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Registry Numbers
MDL Number
MFCD09055426
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Storage & Handling
Storage
-20°C
description Product Description
Used as a selective blocker of voltage-gated potassium channels, particularly Kv7 (KCNQ) channels, in neuroscience research. It enhances neuronal excitability and is applied in studies related to synaptic transmission, epilepsy, and neurodegenerative diseases. Commonly used in electrophysiological experiments to investigate M-current modulation. Also explored for its potential to improve cognitive functions in preclinical models due to its effect on neuronal signaling.
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