Used in research to inhibit the Wnt/β-catenin signaling pathway by targeting tankyrase enzymes. This inhibition stabilizes the β-catenin destruction complex, leading to reduced levels of β-catenin in cells. Commonly applied in studies of cancer biology, particularly in colorectal and other Wnt-driven cancers, to assess tumor growth and cell proliferation. Also utilized in stem cell research and developmental biology to modulate Wnt signaling and study its role in cell differentiation and tissue regeneration.