Used in research for its interaction with adrenergic receptors, particularly as an antagonist at α2-adrenergic receptors. This activity makes it valuable in studies related to neurotransmission, blood pressure regulation, and smooth muscle contraction. It has also been explored for potential effects on sexual function and as a tool in understanding mechanisms of arousal and anxiety in animal models. Due to its structural similarity to yohimbine, it serves as a reference compound in pharmacological comparisons, helping differentiate receptor subtypes and their roles in physiological responses.