(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid

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Reagent Code: #246600
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CAS Number 66338-96-3

science Other reagents with same CAS 66338-96-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 187.18 g/mol
Formula C₅H₅N₃O₃S
badge Registry Numbers
MDL Number MFCD00062754
thermostat Physical Properties
Melting Point 190-192°C
Boiling Point 539.4°C
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of cephalosporin antibiotics, particularly third-generation ones like ceftriaxone and cefotaxime. Its structure enables beta-lactam ring formation, enhancing antimicrobial activity against a broad spectrum of bacteria, including Gram-negative strains. The (Z)-isomer configuration is critical for optimal biological activity. It plays a vital role in improving the pharmacokinetics and stability of the final antibiotic products.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿143.00
inventory 1g
10-20 days ฿360.00
inventory 5g
10-20 days ฿1,380.00

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(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid
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Used as a key intermediate in the synthesis of cephalosporin antibiotics, particularly third-generation ones like ceftriaxone and cefotaxime. Its structure enables beta-lactam ring formation, enhancing antimicrobial activity against a broad spectrum of bacteria, including Gram-negative strains. The (Z)-isomer configuration is critical for optimal biological activity. It plays a vital role in improving the pharmacokinetics and stability of the final antibiotic products.
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