(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid
95%
Reagent
Code: #246600
CAS Number
66338-96-3
science Other reagents with same CAS 66338-96-3
blur_circular Chemical Specifications
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Molecular Information
Weight
187.18 g/mol
Formula
C₅H₅N₃O₃S
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Registry Numbers
MDL Number
MFCD00062754
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Physical Properties
Melting Point
190-192°C
Boiling Point
539.4°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of cephalosporin antibiotics, particularly third-generation ones like ceftriaxone and cefotaxime. Its structure enables beta-lactam ring formation, enhancing antimicrobial activity against a broad spectrum of bacteria, including Gram-negative strains. The (Z)-isomer configuration is critical for optimal biological activity. It plays a vital role in improving the pharmacokinetics and stability of the final antibiotic products.
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