(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
97%
Reagent
Code: #246603
CAS Number
356068-93-4
science Other reagents with same CAS 356068-93-4
blur_circular Chemical Specifications
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Molecular Information
Weight
300.28 g/mol
Formula
C₁₆H₁₃FN₂O₃
thermostat
Physical Properties
Boiling Point
588.4°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in anticancer agents targeting vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR). Its structure enables selective inhibition of abnormal cell signaling pathways in tumors, making it valuable in developing targeted cancer therapies. Also employed in research for structure-activity relationship studies to optimize drug potency and selectivity.
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