((Z)-2-((3S,5R)-3,5-Bis((Tert-Butyldimethylsilyl)Oxy)-2-Methylenecyclohexylidene)Ethyl)Diphenylphosphine Oxide
98%
Reagent
Code: #246810
CAS Number
81522-68-1
science Other reagents with same CAS 81522-68-1
blur_circular Chemical Specifications
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Molecular Information
Weight
582.9 g/mol
Formula
C₃₃H₅₁O₃PSi₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in organic synthesis, particularly in the preparation of complex natural products and pharmaceuticals. Its phosphine oxide functionality enables Horner-Wadsworth-Emmons olefination reactions, allowing stereoselective formation of α,β-unsaturated systems with high (Z)-selectivity. The silyl-protected hydroxyl groups provide stability and compatibility with multi-step synthetic sequences, while allowing selective deprotection for further functionalization. Commonly employed in the synthesis of bioactive molecules such as vitamin D analogs and terpenoids where precise stereochemical control is required.
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