((Z)-2-((3S,5R)-3,5-Bis((Tert-Butyldimethylsilyl)Oxy)-2-Methylenecyclohexylidene)Ethyl)Diphenylphosphine Oxide

98%

Reagent Code: #246810
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CAS Number 81522-68-1

science Other reagents with same CAS 81522-68-1

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Weight 582.9 g/mol
Formula C₃₃H₅₁O₃PSi₂
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as a key intermediate in organic synthesis, particularly in the preparation of complex natural products and pharmaceuticals. Its phosphine oxide functionality enables Horner-Wadsworth-Emmons olefination reactions, allowing stereoselective formation of α,β-unsaturated systems with high (Z)-selectivity. The silyl-protected hydroxyl groups provide stability and compatibility with multi-step synthetic sequences, while allowing selective deprotection for further functionalization. Commonly employed in the synthesis of bioactive molecules such as vitamin D analogs and terpenoids where precise stereochemical control is required.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿10,890.00
inventory 250mg
10-20 days ฿18,140.00
inventory 1g
10-20 days ฿44,540.00

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((Z)-2-((3S,5R)-3,5-Bis((Tert-Butyldimethylsilyl)Oxy)-2-Methylenecyclohexylidene)Ethyl)Diphenylphosphine Oxide
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Used as a key intermediate in organic synthesis, particularly in the preparation of complex natural products and pharmaceuticals. Its phosphine oxide functionality enables Horner-Wadsworth-Emmons olefination reactions, allowing stereoselective formation of α,β-unsaturated systems with high (Z)-selectivity. The silyl-protected hydroxyl groups provide stability and compatibility with multi-step synthetic sequences, while allowing selective deprotection for further functionalization. Commonly employed in the synthesis of bioactive molecules such as vitamin D analogs and terpenoids where precise stereochemical control is required.
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