Used in research settings to measure ADAMTS-13 enzyme activity or antigen levels in human plasma. Helps investigate thrombotic thrombocytopenic purpura (TTP) and other thrombotic microangiopathies by assessing the protease responsible for cleaving von Willebrand factor (VWF). Enables researchers to study VWF multimer regulation, endothelial dysfunction, and hemostatic disorders. Commonly applied in clinical studies exploring the role of ADAMTS-13 deficiency in autoimmune diseases, sepsis, and cardiovascular conditions. Supports development of diagnostic methods and therapeutic monitoring in hematology and vascular biology research.