Used in biomedical research to quantify levels of Aquaporin-2 protein in urine or tissue samples, aiding in the study of water balance disorders such as nephrogenic diabetes insipidus. Enables researchers to investigate the role of AQP-2 in kidney function, hormonal regulation by vasopressin, and conditions involving abnormal water reabsorption. Commonly applied in clinical labs and pharmaceutical studies to monitor disease progression or response to treatment targeting renal water channels.