Not a chemical compound; huCCR8-HEK293 refers to a cell line engineered to express the human CCR8 receptor in HEK293 (human embryonic kidney 293) cells. This cell line is primarily used in biomedical research, especially in drug discovery and functional assays for immunology and oncology. It serves as a model system to study CCR8 receptor signaling, ligand interactions (such as CCL1), and the development of targeted therapies including monoclonal antibodies and small molecule inhibitors. Due to CCR8's role in regulating immune responses—particularly its expression on regulatory T cells (Tregs) in the tumor microenvironment—this cell line is valuable for screening potential immuno-oncology therapeutics aimed at modulating tumor immune evasion.