Used in biomedical research to quantify levels of human coagulation factor XII in plasma or serum samples. Enables study of contact activation pathway and its role in thrombosis, inflammation, and hemostasis. Commonly applied in diagnostic laboratories and pharmaceutical research to assess Factor XII deficiency or dysregulation, evaluate anticoagulant therapies, and investigate links between coagulation and immune responses. Supports high-throughput screening and precise measurement in experimental models of clotting disorders.