Used in research to study the CXCR4 chemokine receptor's role in immune cell signaling, cancer metastasis, and HIV infection. This cell line serves as a model system for screening potential therapeutic agents targeting CXCR4, such as inhibitors for cancer or antiviral drugs. It is also employed in drug development to evaluate receptor activation, internalization, and downstream signaling pathways. Due to stable expression in CHO cells, it supports consistent, high-throughput assays in pharmacology and molecular biology studies.