Used in apoptosis research to quantify levels of ICAD (Inhibitor of Caspase-Activated DNase) in cell lysates or tissue samples. Helps assess the regulation of DNA fragmentation during programmed cell death. Commonly applied in studies of cancer, neurodegenerative diseases, and developmental biology where apoptosis plays a critical role. Enables researchers to monitor cleavage of ICAD by caspases, indicating activation of the apoptotic pathway. Suitable for high-throughput screening of drug candidates that modulate cell death mechanisms. Provides a reliable, sensitive, and specific method to evaluate cellular responses to stress, toxins, or therapeutic agents.