Used in bone metabolism research to measure C-terminal telopeptide fragments of type I collagen, a biomarker for bone resorption. Helps assess osteoclast activity and bone turnover rates in experimental studies. Commonly applied in preclinical evaluation of osteoporosis treatments, anti-resorptive drugs, and metabolic bone disease mechanisms. Provides quantitative data from serum or plasma samples, supporting investigation into bone health, disease progression, and therapeutic efficacy in research settings. Not intended for diagnostic use.