Indium wire is widely used in cryogenic and vacuum applications due to its excellent thermal and electrical conductivity, combined with its softness and malleability. It forms reliable cold welds when compressed between two surfaces, making it ideal for sealing flanges in ultra-high vacuum systems and low-temperature environments such as cryostats and vacuum chambers. The wire is often used as a gasket material that conforms easily under pressure, creating hermetic seals without requiring high torque or heat. In semiconductor manufacturing and research, indium wire serves as a bonding material for creating electrical interconnects, especially in low-temperature devices like superconducting circuits and infrared detectors. Its high purity minimizes contamination and ensures consistent performance in sensitive applications. It is also employed in thermal interface materials where efficient heat transfer is critical. When compressed between a heat source and a heat sink, indium wire improves thermal coupling by filling microscopic gaps and voids, enhancing overall heat dissipation in high-performance electronics and optoelectronic devices. Additionally, indium wire is used in specialized soldering and indium bumping processes, particularly where lead-free, low-melting-point joining is required. Its ability to bond dissimilar materials, including glass, ceramics, and metals, makes it valuable in advanced packaging and microelectronic assembly.